AAAA weed Canada smoking was linked to testicular cancer
Smoking aaaa weed Canada is a frequent occurrence today. The use of this substance grows over time. In some countries, marijuana is an illicit drug and its cultivation, sale and use are punishable by law. In other countries, it is legalized for medical purposes, while in others it is allowed for recreational use. However, apart from the psychoactive effects of cannabis itself, there is a carcinogenic aspect to its use. Burning marijuana, like all plant materials, produces smoke that has a recognized carcinogenic status.
The studies reviewed by the authors of the article considered possible links between cannabis smoking and several types of cancer - testicular, lung, oral, and head and neck cancer. It was found that a significant connection was found with testicular cancer, but none of the other three diseases. In study participants who had used cannabis daily for 10 years, the risk of this cancer had increased by 36%.
Testicular cancer is a fairly rare disease: according to the American National Rare Diseases Organization, testicular cancer accounts for only one percent of all cancer cases in men. And it is the most common cancer among young men aged 15 to 35 years. Every year, approximately 8,850 men in the United States face this diagnosis. Although it is well curable when diagnosed on time, testicular cancer is a risk of death. Chemotherapy and radiotherapy, surgical treatment, and the risk of losing the ability to spermogenesis (up to 50% of patients) all indicate that testicular cancer should be noticed in time, or better - prevented.
Scientists point out that further research in this area is needed. Current work, due to its overview nature, only indicates the fact itself. At this point, researchers do not know why none of the other three diseases have shown a connection with smoking marijuana.
The results, in particular, may be influenced by the ethnic composition of the participants, as well as the region where they live: the authors note that they have only worked with English-speaking studies. In addition, the habits and substances of consumers half a century ago may be very different from those of modern consumers.
However, the work provides insight into how men can be affected by long-term smoking of aaaa weed Canada. Given the medical use of cannabinoids and new, under-researched methods of use such as waking, more research in this area is needed.
Hemp plants contain many dozens of cannabinoids, the main ones being tetrahydrocannabinol (TNS), which stimulates appetite, has anti-emetic, analgesic and, of course, psychoactive effects; and similar cannabidiol (CBD), which is not psychoactive but can reduce anxiety.
The Cannabis sativa genome was studied by teams of Tim Hughes from the University of Toronto, Canada, and Harm van Bakel from Karl Aikan School of Medicine at the Mount Sinai Clinic (ISMMS) in New York. Professor Hugh published a "draft" of the hemp genome back in 2011, but only now has it been established with sufficient accuracy and allows localization of individual genes and non-coding areas on DNA. Thanks to this, scientists have discovered a previously unknown gene that encodes a protein that synthesizes another cannabisoid of cannabis - cannabis chromene (CBC).
Well, the genes of syntheses involved in the synthesis of TNS and CBD, were located on a fairly large (more than 250 thousand bases) section of DNA, saturated with retrotransposons - mobile genetic elements that do not carry any functional load in the body, but can be stored and reproduced in its DNA. This area, in turn, is surrounded by long (up to 40 million bases) repetitions. This structure is characteristic of viral genomes embedded in the host's DNA.
It happens all the time in nature; the genome of all eukaryotes is full of fragments of ancient viruses, and in our own DNA retrotransposons account for more than 40 per cent. These fragments often remain inactive in the genome and sometimes acquire new properties, and the host begins to use them for its own purposes. This also seems to have happened to cannabis: millions of years ago, the plant was infected https://gg4.store/product-category/indica/ with a virus that introduced the gene protein, the ancestor of TNS and CBD synthase. This ability proved to be useful to it, and over time the plant began to actively use it.
Scientists note that the structure of the site containing the genes TNS and CBD, stimulates the recombination of the chromosome and thus increases its variability. Perhaps that is why by now the plant is able to synthesize more than a hundred different cannabinoids.